A significant amount of people with chronic pain end up with a diagnosis of fibromyalgia. Some patients have the known signs of tender points, while others experience more diffuse pain that is not localized to one specific anatomic area.
There are plenty of medication options for the treatment of fibromyalgia, however, a lot of them simply do not work and are not FDA approved. Whether or not a medication is FDA approved is not necessarily a litmus test for success. In addition, even if the medication is FDA approved for one indication, they can successfully be used many times off label for other conditions.