There are approximately 26 million people in the United States living with chronic kidney disease today and millions more who are at risk of developing it. This is a dangerous and serious disease that should be diagnosed and treated as soon as possible to prevent a rapid progression. It works by reducing, and eventually eliminating, the ability of the kidneys to filter waste products from the bloodstream. In time, the kidneys fail entirely, requiring dialysis or a kidney transplant. Factors that create a higher risk of chronic kidney disease include diabetes, hypertension and family history. Groups of people who have a higher incidence of kidney disease include those of African-American, Hispanic, Pacific Islander or Native American descent.